A novel mouse model of PEDF-associated serious liver inflammation, hepatic tumorigenesis and cardiovascular injury mimics human nonalcoholic steatohepatitis

Xinghui Li; Haiping Wang; Yandi Wu; Li Zou; Shijie Deng; Xinlu Fu; Tongsheng Huang; Conghui Shen; Teng Wu; Weibin Cai

doi:10.1016/j.gendis.2023.01.011

A novel mouse model of PEDF-associated serious liver inflammation, hepatic tumorigenesis and cardiovascular injury mimics human nonalcoholic steatohepatitis

Genes Dis. 2023 Mar 23;11(1):11-14. doi: 10.1016/j.gendis.2023.01.011. eCollection 2024 Jan.

Authors

Xinghui Li^{1

2}, Haiping Wang^{1

2}, Yandi Wu^{1

2}, Li Zou³, Shijie Deng^{1

2}, Xinlu Fu^{1

2}, Tongsheng Huang^{1

2}, Conghui Shen^{1

2}, Teng Wu^{1

2}, Weibin Cai^{1

2

4}

Affiliations

¹ Guangdong Engineering & Technology Research Center for Disease-Model Animals, Laboratory Animal Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
² Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
³ School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong 510006, China.
⁴ Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong 518107, China.

No abstract available