Cystic fibrosis year in review 2022

Pediatr Pulmonol. 2023 Nov;58(11):3013-3022. doi: 10.1002/ppul.26641. Epub 2023 Aug 18.

Abstract

Remarkable medical advancements have been made for people with cystic fibrosis (CF) in recent years, with an abundance of research continuing to be conducted worldwide. With concern for limitations in access to highly effective CFTR modulators, as well as the recent Coronavirus Disease-19 pandemic, there has been a consistent effort to understand and improve CF screening, disease burden, diagnosis, and management. Our aim in this review is to present articles from 2022 with an emphasis on clinically relevant studies. We hope this will serve as a broad overview of the research published in the past year.

Keywords: CFTR modulators; cystic fibrosis; lung transplantation; newborn screening; obesity; pancreatic insufficiency; pulmonary exacerbations.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Cost of Illness
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics
  • Cystic Fibrosis* / diagnosis
  • Cystic Fibrosis* / genetics
  • Humans
  • Mutation

Substances

  • Cystic Fibrosis Transmembrane Conductance Regulator