Breast Cancer and Lifestyle Factors: Umbrella Review

Hematol Oncol Clin North Am. 2024 Feb;38(1):137-170. doi: 10.1016/j.hoc.2023.07.005. Epub 2023 Aug 26.

Abstract

Lifestyle factors play a major role in the risk of breast cancer. This review aimed to examine the size of the effect of select lifestyle factors on risk for breast cancer and assess the quality of existing evidence. The authors performed an umbrella review of systematic reviews. The authors found an increased risk for breast cancer associated with obesity, alcohol intake, and smoking and a decreased risk due to physical activity. The evidence for sleep disruption and duration indicates risk for breast cancer, but it is limited in size, statistical significance, and quality of evidence.

Keywords: Body mass index; Breast cancer; Obesity; Overweight; Physical activity; Sleep; Smoking; Waist-to-hip ratio.

Publication types

  • Systematic Review

MeSH terms

  • Body Mass Index
  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / etiology
  • Female
  • Humans
  • Life Style
  • Obesity / complications
  • Obesity / epidemiology
  • Risk Factors
  • Systematic Reviews as Topic