Microbial Primer: LuxR-LuxI Quorum Sensing

Microbiology (Reading). 2023 Sep;169(9):001343. doi: 10.1099/mic.0.001343.

Abstract

Quorum sensing is a term describing bacterial cell-to-cell communication systems for monitoring and responding to changes in population density. This primer serves as an introduction to the canonical LuxR-LuxI-type quorum sensing circuits common to many species of Gram-negative bacteria. Quorum sensing can synchronize behaviours across a community. Different species employ quorum sensing strategies to control specific behaviours such as bioluminescence, virulence factor production, secondary metabolite production, and biofilm formation.

Keywords: quorum sensing.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Quorum Sensing*
  • Trans-Activators / genetics
  • Virulence Factors*

Substances

  • Virulence Factors
  • Trans-Activators