Rapid diagnosis of type III group B streptococcal meningitis by latex particle agglutination

J Pediatr. 1979 Aug;95(2):202-5. doi: 10.1016/s0022-3476(79)80651-4.

Abstract

A latex particle agglutination assay was developed to detect type III group B streptococcal antigen in cerebrospinal fluid. Agglutination was observed in each of 12 initial and 54% of 26 subsequent CSF specimens obtained a mean of 53 hours after the institution of antimicrobial therapy. Latex agglutination was more sensitive than countercurrent immunoelectrophoresis for the detection of type III group B streptococcal antigen in CSF from neonates and young infants with meningitis.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antigens, Bacterial / analysis
  • Counterimmunoelectrophoresis
  • Humans
  • Infant
  • Infant, Newborn
  • Latex Fixation Tests
  • Meningitis / cerebrospinal fluid
  • Meningitis / diagnosis*
  • Streptococcal Infections / cerebrospinal fluid
  • Streptococcal Infections / diagnosis*
  • Streptococcus agalactiae

Substances

  • Antigens, Bacterial