Intraoperative cardiac arrest due to allergic acute coronary syndrome (Kounis syndrome) triggered by cephalosporin

Ann Card Anaesth. 2023 Apr-Jun;26(2):219-222. doi: 10.4103/aca.aca_302_20.

Abstract

An acute coronary syndrome due to mast-cell activation in the presence of an allergen is known as Kounis Syndrome (KS). This relatively new entity of KS is being increasingly recognized among allergists, cardiologists, and emergency physicians; however, it is not well-known among anesthesiologists. We report here, a case of type 2 KS due to antibiotic administration causing sudden perioperative cardiac arrest.

Keywords: Allergy; Kounis Syndrome; allergic myocardial infarction; anaphylaxis; cardiac arrest.

Publication types

  • Case Reports

MeSH terms

  • Acute Coronary Syndrome* / complications
  • Anaphylaxis* / chemically induced
  • Cephalosporins
  • Heart Arrest* / chemically induced
  • Heart Arrest* / therapy
  • Humans
  • Kounis Syndrome* / complications

Substances

  • Cephalosporins