Very-late-onset interstitial pneumonia suspected to be related to liver transplantation more than 10 years ago

Tsuneyuki Oda; Hideya Kitamura; Koji Okudela; Tamiko Takemura; Takashi Ogura

doi:10.1016/j.resinv.2023.07.002

Very-late-onset interstitial pneumonia suspected to be related to liver transplantation more than 10 years ago

Respir Investig. 2023 Nov;61(6):682-686. doi: 10.1016/j.resinv.2023.07.002. Epub 2023 Sep 15.

Authors

Tsuneyuki Oda¹, Hideya Kitamura², Koji Okudela³, Tamiko Takemura⁴, Takashi Ogura²

Affiliations

¹ Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan. Electronic address: [email protected].
² Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.
³ Department of Pathobiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
⁴ Department of Pathology, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan.

PMID: 37708633
DOI: 10.1016/j.resinv.2023.07.002

Abstract

Pulmonary complications after liver transplantation are common in the postoperative period, becoming less frequent in the subsequent months, and rare after 1 year. However, we encountered two cases of very-late-onset interstitial pneumonia suspected to be related to liver transplantation after 14 and 15 years. Both patients presented with non-specific interstitial pneumonia patterns, which significantly improved with corticosteroid therapy. Physicians should be aware of such complications and monitor them after liver transplantation.

Keywords: Corticosteroids; Interstitial pneumonia; Liver transplantation; Solid organ transplantation; Tacrolimus.

Publication types

Case Reports

MeSH terms

Humans
Liver Transplantation* / adverse effects
Lung Diseases, Interstitial* / diagnostic imaging
Lung Diseases, Interstitial* / etiology