Malignant cardiac neoplasms and associated malignancies over 16 years in the USA

Neiberg A Lima; Kamil Cwikla; Kristina Byers-Spencer; Ian Crumm; Dhruvil Patel; Cuyler Huffman; Theresa N McGoff; Jeffrey Young; Thomas A Melgar; Nicholas Helmstetter

doi:10.1016/j.jjcc.2023.09.004

Malignant cardiac neoplasms and associated malignancies over 16 years in the USA

J Cardiol. 2024 Jun;83(6):377-381. doi: 10.1016/j.jjcc.2023.09.004. Epub 2023 Sep 13.

Authors

Affiliations

¹ Department of Internal Medicine, Division of Cardiology, Wayne State University, Detroit, MI, USA. Electronic address: [email protected].
² Department of Internal Medicine, Loyola University Medical Center, Maywood, IL, USA.
³ Departments of Internal Medicine and Pediatrics, Spectrum Health/Michigan State University, Grand Rapids, MI, USA.
⁴ Departments of Pediatrics, Adolescent and Internal Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.
⁵ Wayne State University, School of Medicine, Detroit, MI, USA.
⁶ Department of Epidemiology and Biostatistics, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.
⁷ Department of Biomedical Informatics, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.

PMID: 37714265
DOI: 10.1016/j.jjcc.2023.09.004

Abstract

Background: Malignant cardiac neoplasms (MCNs), both primary and metastatic, are rare with few epidemiologic studies.

Methods: This retrospective study used the Healthcare Utilization Project/Nationwide Inpatient Sample database from 2002 to 2018 to evaluate the co-occurrences with other malignancies, and mortality of MCNs in the USA.

Results: The data contained 7207 weighted discharges of MCN. Median patient age was 51.4 years, 52.29 % were male, in-hospital mortality was 10.51 %, mean cost of hospitalization was $34,280 USD. Lung, mediastinum, and airways were the most common primary cancers associated with metastatic MCN.

Conclusions: MCN are rare in the USA, however they carry a high in-hospital mortality, high morbidity, and hospital cost.

Keywords: Epidemiology; Malignant cardiac neoplasms; United States of America.

MeSH terms

Female
Heart Neoplasms* / epidemiology
Hospital Mortality
Hospitalization*
Humans
Male
Middle Aged
Retrospective Studies
United States / epidemiology