The diversity of cGLR receptors: shedding new light on innate immunity

C Jessica E Metcalf; Alexander E Downie

doi:10.1016/j.it.2023.09.001

The diversity of cGLR receptors: shedding new light on innate immunity

Trends Immunol. 2023 Oct;44(10):763-765. doi: 10.1016/j.it.2023.09.001. Epub 2023 Sep 15.

Authors

C Jessica E Metcalf¹, Alexander E Downie²

Affiliations

¹ Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA. Electronic address: [email protected].
² Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.

PMID: 37718173
DOI: 10.1016/j.it.2023.09.001

Abstract

The characterization of a new group of innate pattern recognition receptors detected in >500 species across the tree of life by Li et al. reveals surprising commonalities and peculiarities shared with other innate receptors. Receptor diversity within and among species opens the way to reconsidering the costs and benefits of innate immune recognition.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Humans
Immunity, Innate*
Receptors, Pattern Recognition*

Substances

Receptors, Pattern Recognition