Clinical Outcomes of Acutely Ill Children According to Cycle Threshold Values of Respiratory Viruses Detected by Multiplex PCR Testing

Suvi Mattila; Minna Honkila; Niko Paalanne; Vesa Mäki-Koivisto; Kimmo Halt; Tuomas Jartti; Olli Ruuskanen; Matti Waris; Tytti Pokka; Terhi Tapiainen

doi:10.1093/jpids/piad071

Clinical Outcomes of Acutely Ill Children According to Cycle Threshold Values of Respiratory Viruses Detected by Multiplex PCR Testing

J Pediatric Infect Dis Soc. 2023 Oct 28;12(10):549-552. doi: 10.1093/jpids/piad071.

Authors

Suvi Mattila^{1

2}, Minna Honkila^{1

2}, Niko Paalanne^{1

2}, Vesa Mäki-Koivisto³, Kimmo Halt^{1

2}, Tuomas Jartti^{1

2

4}, Olli Ruuskanen⁴, Matti Waris⁵, Tytti Pokka^{2

6}, Terhi Tapiainen^{1

2

7}

Affiliations

¹ Department of Pediatrics and Adolescent Medicine, Oulu University Hospital, Oulu, Finland.
² Research Unit of Clinical Medicine and Medical Research Center Oulu, University of Oulu, Oulu, Finland.
³ Clinical Microbiology Laboratory, Nordlab, Oulu, Finland.
⁴ Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.
⁵ Institute of Biomedicine, University of Turku, Turku, Finland.
⁶ Research Service Unit, Oulu University Hospital, Oulu, Finland.
⁷ Biocenter Oulu, University of Oulu, Oulu, Finland.

Abstract

In this cohort study of 800 children attending a pediatric emergency department at Oulu University Hospital, Finland with fever or respiratory symptoms, the cycle threshold values of point-of-care multiplex polymerase chain reaction testing for respiratory viruses were not associated with hospitalization, respiratory support, or need for intensive care.

Keywords: cycle threshold values; multiplex polymerase chain reaction; pediatric emergency department; point-of-care testing; respiratory viruses.

© The Author(s) 2023. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: [email protected].

MeSH terms

Child
Cohort Studies
Humans
Infant
Multiplex Polymerase Chain Reaction
Respiratory Tract Infections* / diagnosis
Virus Diseases* / diagnosis
Viruses* / genetics

Abstract

MeSH terms

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