Irritant asthma and work: cases from the UK SWORD reporting scheme from 1999 to 2018

Occup Environ Med. 2023 Oct;80(10):553-557. doi: 10.1136/oemed-2023-108884. Epub 2023 Sep 28.

Abstract

Background: Acute irritant asthma is a preventable health consequence of a workplace exposure and has a number of adverse outcomes. While cases and case series are reported, little is known about the causes and incidence of this condition over prolonged periods of time.

Aims: We aimed to estimate the reported incidence of irritant asthma referred to a national reporting scheme, and how this has changed over time.

Methods: Cases of irritant asthma reported to SWORD, the UK-based Surveillance of Work-related Occupational Respiratory Diseases scheme, were grouped into four 5-year time periods from 1999 onwards. Likely causative exposures, job, work sector and incidence rates were analysed over time.

Results: 307 actual cases equated to 1066 estimated cases; actual cases had a mean age of 46 years (SD 17.8); 70.7% were male. The annual incidence fell from 1.98 per million employed in the first 5-year period, to 0.56 in the most recent. Eleven occupational codes were associated with six or more attributed cases, and between them accounted for 38% of all cases. Thirteen exposure categories were associated with five or more cases. These were formaldehyde (n=5), cutting oils and coolants (n=6), isocyanates (n=6), pesticides and herbicides (n=6), welding fumes (n=7), paints (n=7), solder and colophony (n=7), solvents (n=9), fuel oil, diesel and ill-defined fumes (n=10), chlorine and hypochlorites (n=15), acids (n=23), smoke (n=25) and cleaning products and sterilising agents (n=39).

Conclusions: While the incidence of irritant asthma may have fallen, cases are persistently attributed to well-described causes. A persistence of cases attributed to cleaning agents was seen.

Keywords: asthma; epidemiology; occupational health; respiratory; respiratory function tests.

MeSH terms

  • Asthma* / epidemiology
  • Asthma* / etiology
  • Female
  • Humans
  • Incidence
  • Irritants / adverse effects
  • Male
  • Middle Aged
  • Occupational Diseases* / epidemiology
  • Occupational Diseases* / etiology
  • Occupational Exposure* / adverse effects
  • United Kingdom / epidemiology

Substances

  • Irritants