Clinical and Surgical Approach for Cerebral Cortical Dysplasia

Marcelo Volpon Santos; Camila Araujo Bernardino Garcia; Ana Paula Andrade Hamad; Ursula Thome Costa; Americo Ceiki Sakamoto; Antonio Carlos Dos Santos; Helio Rubens Machado

doi:10.1007/978-3-031-36785-4_12

Clinical and Surgical Approach for Cerebral Cortical Dysplasia

Adv Tech Stand Neurosurg. 2023:48:327-354. doi: 10.1007/978-3-031-36785-4_12.

Authors

Marcelo Volpon Santos^{1

2}, Camila Araujo Bernardino Garcia³, Ana Paula Andrade Hamad³, Ursula Thome Costa³, Americo Ceiki Sakamoto³, Antonio Carlos Dos Santos³, Helio Rubens Machado³

Affiliations

¹ Center for Pediatric Epilepsy Surgery (CIREP), Ribeirão Preto Medical School, University Hospital, University of São Paulo, São Paulo, SP, Brazil. [email protected].
² Department of Surgery and Anantomy, Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil. [email protected].
³ Center for Pediatric Epilepsy Surgery (CIREP), Ribeirão Preto Medical School, University Hospital, University of São Paulo, São Paulo, SP, Brazil.

PMID: 37770690
DOI: 10.1007/978-3-031-36785-4_12

Abstract

The present article describes pathophysiological and clinical aspects of congenital malformations of the cerebral tissue (cortex and white matter) that cause epilepsy and very frequently require surgical treatment. A particular emphasis is given to focal cortical dysplasias, the most common pathology among these epilepsy-related malformations. Specific radiological and surgical features are also highlighted, so a thorough overview of cortical dysplasias is provided.

Keywords: Cortical dysplasia; Epilepsy; Epilepsy surgery; Malformations of cortical development; Outcome.

MeSH terms

Cerebral Cortex / diagnostic imaging
Epilepsy* / etiology
Focal Cortical Dysplasia*
Humans
Magnetic Resonance Imaging / adverse effects
Malformations of Cortical Development* / complications