Image-guided preplanning workflow for high-dose-rate interstitial brachytherapy for gynecological malignancies

Brachytherapy. 2024 Jan-Feb;23(1):25-34. doi: 10.1016/j.brachy.2023.09.005. Epub 2023 Sep 28.

Abstract

Purpose: To demonstrate image-guided preplan workflows for high-dose-rate (HDR) brachytherapy for advanced gynecological malignancies.

Methods and materials: Two different preplanning scenarios are presented: (1) CT- or MRI-based preplan with partial applicator in place; (2) Preplans generated from prior fractions. The first scenario can be applied to Syed-Neblett template-based implants or hybrid brachytherapy applicators, while the second scenario applies to hybrid applicators. Both scenarios use MRI or CT images acquired with the applicator in place to demonstrate tumor and applicator relative locations and therefore, provide the ability to show optimized suggested needle positions including the implant depths before the actual insertion.

Results: The preplanning techniques have demonstrated feasibility and shown five areas of potential improvement: (1) shorter procedure time, (2) decreased number of total needles inserted, (3) shorter physician tumor contour time, (4) shorter planning time, and (5) evaluation of appropriateness for brachytherapy.

Conclusions: The use of image-guided brachytherapy preplanning improves clinical efficiency and is recommended for consideration for adaptation into clinical workflows for HDR interstitial and hybrid brachytherapy.

Keywords: Brachytherapy; Gynecological malignancy; Interstitial brachytherapy; Preplan.

MeSH terms

  • Brachytherapy* / methods
  • Female
  • Genital Neoplasms, Female* / diagnostic imaging
  • Genital Neoplasms, Female* / radiotherapy
  • Humans
  • Needles
  • Prostheses and Implants
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / methods
  • Workflow