Isolated Skull Metastasis With Unusual Spiculated Periosteal Reaction From Rectal Cancer Resembling Osteosarcoma on FDG PET/CT

Mingyuan Liu; Aisheng Dong; Changjin Zuo; Yan Zhu; Xiaoling Fu

doi:10.1097/RLU.0000000000004859

Isolated Skull Metastasis With Unusual Spiculated Periosteal Reaction From Rectal Cancer Resembling Osteosarcoma on FDG PET/CT

Clin Nucl Med. 2023 Nov 1;48(11):1006-1008. doi: 10.1097/RLU.0000000000004859. Epub 2023 Sep 18.

Authors

Mingyuan Liu¹, Aisheng Dong², Changjin Zuo², Yan Zhu³, Xiaoling Fu⁴

Affiliations

¹ From the Department of Neurology, Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine.
² Departments of Nuclear Medicine.
³ Pathology, The First Affiliated Hospital of Naval Medical University.
⁴ Department of Medical Oncology, Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

PMID: 37793159
DOI: 10.1097/RLU.0000000000004859

Abstract

We describe FDG PET/CT findings in a case of isolated skull metastasis with spiculated periosteal reaction from rectal mucinous adenocarcinoma 8 years after proctectomy. The skull metastasis showed heterogeneous FDG uptake and multiple short spicules of bone producing the sunburst appearance resembling primary osteosarcoma or Ewing sarcoma. Familiarity with this atypical imaging appearance of the bone metastasis from rectal cancer may be helpful for the diagnosis and differential diagnosis.

Publication types

Case Reports

MeSH terms

Bone Neoplasms* / diagnostic imaging
Bone Neoplasms* / pathology
Fluorodeoxyglucose F18
Humans
Osteosarcoma* / diagnostic imaging
Osteosarcoma* / pathology
Positron Emission Tomography Computed Tomography / methods
Radiopharmaceuticals
Rectal Neoplasms* / diagnostic imaging
Rectal Neoplasms* / pathology
Skull

Substances

Fluorodeoxyglucose F18
Radiopharmaceuticals