Use of vitamin D with anti-osteoporotic drugs: are available clinical trials telling us the whole story?

Endocrine. 2024 Feb;83(2):342-348. doi: 10.1007/s12020-023-03551-z. Epub 2023 Oct 10.

Abstract

There is a strong rationale for using vitamin D in combination with anti-osteoporotic drugs. Still, available trials do not give clear indications in this setting, presenting a suboptimal and heavily inhomogeneous experimental design. Health authorities should revise requirements for using vitamin D in anti-osteoporotic drug trials to maximise their effect and produce reliable indications for clinical practice in this setting.

MeSH terms

  • Clinical Trials as Topic
  • Humans
  • Osteoporosis* / drug therapy
  • Vitamin D* / therapeutic use

Substances

  • Vitamin D