Resolving the tissue response to neoadjuvant chemotherapy in rectal cancer

Justin A Shyer; Shannon J Turley; Louis Vermeulen

doi:10.1016/j.xcrm.2023.101232

Resolving the tissue response to neoadjuvant chemotherapy in rectal cancer

Cell Rep Med. 2023 Oct 17;4(10):101232. doi: 10.1016/j.xcrm.2023.101232.

Authors

Justin A Shyer¹, Shannon J Turley¹, Louis Vermeulen²

Affiliations

¹ Genentech Inc, South San Francisco, CA, USA.
² Genentech Inc, South San Francisco, CA, USA; Cancer Center Amsterdam (CCA) & Oncode Institute, Amsterdam UMC, Amsterdam, the Netherlands. Electronic address: [email protected].

Abstract

In this issue of Cell Reports Medicine, Qin et al.¹ present a comprehensive single-cell transcriptomics analysis of the tumor microenvironment of rectal cancer tumors before and after neoadjuvant chemotherapy.

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MeSH terms

Humans
Neoadjuvant Therapy*
Neoplasm Staging
Rectal Neoplasms* / drug therapy
Rectal Neoplasms* / pathology
Tumor Microenvironment