Towards decoding the space-time continuum of pregnancy

Kristin Thiele; Petra Clara Arck

doi:10.1016/j.it.2023.09.011

Towards decoding the space-time continuum of pregnancy

Trends Immunol. 2023 Nov;44(11):859-861. doi: 10.1016/j.it.2023.09.011. Epub 2023 Oct 20.

Authors

Kristin Thiele¹, Petra Clara Arck²

Affiliations

¹ Division of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: [email protected].
² Division of Experimental Feto-Maternal Medicine, Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: [email protected].

PMID: 37867113
DOI: 10.1016/j.it.2023.09.011

Abstract

Pregnancy is likely nature's most elaborate model of dynamic adaptations occurring over a distinct period of time at specific sites of the maternal body. Spatially-resolved transcriptomic analyses now enable the comprehensive decoding of these dynamic adaptations during the early onset stages of mammalian pregnancies and throughout fetal development.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Female
Fetal Development*
Mammals*
Pregnancy