Towards the Definition of Radiomic Features and Clinical Indices to Enhance the Diagnosis of Clinically Significant Cancers in PI-RADS 4 and 5 Lesions

Cancers (Basel). 2023 Oct 12;15(20):4963. doi: 10.3390/cancers15204963.

Pietro Andrea Bonaffini^{1

2}, Elisabetta De Bernardi^{3

4}, Andrea Corsi^{1

2}, Paolo Niccolò Franco^{1

2}, Dario Nicoletta¹, Riccardo Muglia^{1

2}, Giovanna Perugini¹, Marco Roscigno^{2

5}, Mariaelena Occhipinti⁶, Luigi Filippo Da Pozzo^{2

5}, Sandro Sironi^{1

2}

¹ Department of Radiology, ASST Papa Giovanni XXIII, Piazza OMS, 24127 Bergamo, BG, Italy.
² School of Medicine, University of Milano-Bicocca, Piazza dell'Ateneo Nuovo, 1, 20126 Milan, MI, Italy.
³ Medicine and Surgery Department, Via Cadore, 48, 20900 Monza, MB, Italy.
⁴ Interdepartmental Research Centre Bicocca Bioinformatics Biostatistics and Bioimaging Centre-B4, University of Milano-Bicocca, Via Follereau 3, 20854 Vedano al Lambro, MB, Italy.
⁵ Department of Urology, ASST Papa Giovanni XXIII, Piazza OMS, 1, 24127 Bergamo, BG, Italy.
⁶ Radiomics, Boulevard Patience et Beaujonc 3, 4000 Liège, Belgium.

Abstract

Prostate cancer (PC) is the most frequently diagnosed cancer among adult men, and its incidence is increasing worldwide [...].

Keywords: PI-RADS v.2.1; clinically significant cancers; multiparametric prostate MRI; prostate cancer; radiomics.

This research received no external funding.