A tale of two cells: Regulatory T cell-microglia cross-talk in the ischemic brain

Sci Transl Med. 2023 Nov 8;15(721):eadj0052. doi: 10.1126/scitranslmed.adj0052. Epub 2023 Nov 8.

Authors

Alessio Ricci¹, Arthur Liesz^{1

2}

Affiliations

¹ Institute for Stroke and Dementia Research, University Medical Center Munich, Munich, Germany.
² Munich Cluster for Systems Neurology, Munich, Germany.

PMID: 37939163
DOI: 10.1126/scitranslmed.adj0052

Abstract

Regulatory T cells exert a beneficial immunomodulatory effect on poststroke neuroinflammation that is amplified by microglial cells.

Publication types

Review

MeSH terms

Brain
Brain Ischemia*
Humans
Microglia*
Signal Transduction
T-Lymphocytes, Regulatory