Treatment of Oral Dysplasia

Earl Clarkson; Reza Hadioonzadeh; Scott M Peters

doi:10.1016/j.cden.2023.07.008

Treatment of Oral Dysplasia

Dent Clin North Am. 2024 Jan;68(1):133-149. doi: 10.1016/j.cden.2023.07.008. Epub 2023 Aug 23.

Authors

Earl Clarkson¹, Reza Hadioonzadeh², Scott M Peters³

Affiliations

¹ Oral and Maxillofacial Surgery, Woodhull Medical Center, Brooklyn, NY, USA.
² Oral and Maxillofacial Pathology, Geisinger Medical Center, Wilkes-Barre, PA, USA.
³ Oral and Maxillofacial Surgery, Woodhull Medical Center, Brooklyn, NY, USA. Electronic address: [email protected].

PMID: 37951630
DOI: 10.1016/j.cden.2023.07.008

Abstract

Oral epithelial dysplasia refers to a premalignant lesion of the oral cavity. The diagnosis of dysplasia is rendered via pathologic assessment of diseased tissue. There are many different premalignant conditions identified in the oral cavity. These include leukoplakias, erythroplakias, proliferative verrucous leukoplakia, oral submucosal fibrosis, actinic cheilitis, and lichen planus. This article will discuss these different conditions and how they are diagnosed. It will also review the treatment for these entities.

Keywords: Actinic cheilitis; Dysplasia; Erythroplakia; Leukoplakia; Lichen planus; Oral submucosal fibrosis; Proliferative verrucous leukoplakia; Squamous cell carcinoma.

Publication types

Review

MeSH terms

Cell Transformation, Neoplastic / pathology
Cheilitis*
Humans
Hyperplasia
Leukoplakia, Oral / diagnosis
Leukoplakia, Oral / pathology
Leukoplakia, Oral / therapy
Lichen Planus, Oral* / diagnosis
Lichen Planus, Oral* / therapy
Mouth Neoplasms* / diagnosis
Mouth Neoplasms* / pathology
Mouth Neoplasms* / therapy
Precancerous Conditions* / diagnosis
Precancerous Conditions* / pathology
Precancerous Conditions* / therapy