In vivo evolution to high-level cefiderocol resistance of NDM-1-producing Klebsiella pneumoniae, followed by intra-hospital cross-transmission

Clin Microbiol Infect. 2024 Mar;30(3):398-400. doi: 10.1016/j.cmi.2023.11.005. Epub 2023 Nov 17.
No abstract available

Keywords: Carbapenemase; CirA; Fitness; Metallo-β-lactamase; Siderophore receptor.

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics
  • Cefiderocol*
  • Hospitals
  • Humans
  • Klebsiella Infections* / microbiology
  • Klebsiella pneumoniae / genetics
  • Microbial Sensitivity Tests
  • beta-Lactamases / genetics

Substances

  • Cefiderocol
  • Anti-Bacterial Agents
  • beta-Lactamases
  • Bacterial Proteins