An Intraislet Paracrine Signaling Pathway That Enables Glucagon to Stimulate Pancreatic β-Cells
Diabetes
.
2023 Dec 1;72(12):1748-1750.
doi: 10.2337/dbi23-0023.
Authors
Alejandro Caicedo
1
,
Mark O Huising
2
3
,
Jürgen Wess
4
Affiliations
1
Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL.
2
Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, Davis, CA.
3
Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, Davis, CA.
4
Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
PMID:
37983525
PMCID:
PMC10658067
DOI:
10.2337/dbi23-0023
No abstract available
MeSH terms
Glucagon / metabolism
Glucagon-Secreting Cells* / metabolism
Insulin / metabolism
Insulin-Secreting Cells* / metabolism
Islets of Langerhans* / metabolism
Paracrine Communication
Substances
Glucagon
Insulin
Grants and funding
R01 DK111538/DK/NIDDK NIH HHS/United States
R01 DK132597/DK/NIDDK NIH HHS/United States
U01 DK120456/DK/NIDDK NIH HHS/United States
R01 DK084321/DK/NIDDK NIH HHS/United States
R01 DK110276/DK/NIDDK NIH HHS/United States
R01 DK113093/DK/NIDDK NIH HHS/United States