DiabeText, a mobile health intervention to support medication taking and healthy lifestyle in adults with type 2 diabetes: Study protocol for a randomized controlled trial

Contemp Clin Trials. 2024 Jan:136:107399. doi: 10.1016/j.cct.2023.107399. Epub 2023 Nov 22.

Abstract

Aim: To evaluate the effectiveness of DiabeText, a low-intensity, multifaceted, mobile health (mHealth) intervention to support medication taking and lifestyle change targeted to people with type 2 diabetes (T2D).

Design: Phase III, 12-months, two-arm (1:1 allocation ratio), randomized parallel-group trial.

Methods: We will recruit 740 adults with glycated hemoglobin (A1c) >8% (>64 mmol/mol) and with at least one prescription of a non-insulin antidiabetic drug. They will be allocated to a control (usual care) group or an intervention (DiabeText messaging intervention) group. The primary outcome measure will be A1c at 12 months follow-up. Secondary outcomes will include medication possession ratio and behavioral and psychological outcomes.

Discussion: Recent trials suggest that digital health interventions can effectively support diabetes self-management improving T2D control and reducing important T2D complications. In Spain this type of interventions is understudied.

Impact: This trial will strengthen the evidence base of the impact of mHealth interventions to support diabetes self-management. If effective, DiabeText may offer a low-cost and highly scalable strategy to improve health at the population level in a sustainable way.

Trial registration: ClinicalTrials.gov identifier NCT05006872; Official Title: Supporting People with Type 2 Diabetes in Effective Use of their Medicine Through a System Comprising Mobile Health Technology Integrated with Clinical Care.

Keywords: Diabetes self-management; Glycemic control; Lifestyle behavior; Randomized controlled trial; SMS; Treatment adherence; Type 2 diabetes; mHealth.

Publication types

  • Clinical Trial Protocol
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 2* / drug therapy
  • Diabetes Mellitus, Type 2* / psychology
  • Glycated Hemoglobin
  • Healthy Lifestyle
  • Humans
  • Randomized Controlled Trials as Topic
  • Telemedicine* / methods
  • Text Messaging*

Substances

  • Glycated Hemoglobin

Associated data

  • ClinicalTrials.gov/NCT05006872