Could motor blocks be a therapeutic option for treatment-resistant functional dystonia? A case series of three patients

Eur J Neurol. 2024 Mar;31(3):e16150. doi: 10.1111/ene.16150. Epub 2023 Nov 28.

Abstract

The diagnosis of functional dystonia is challenging because it is difficult to distinguish functional dystonia from other types of dystonia. After diagnostic explanation, multidisciplinary care is recommended, but some patients are resistant to treatments. We used motor blocks in three patients with severe resistant functional dystonia of the upper limbs to test (i) whether joint contracture was present and (ii) whether motor blocks have a therapeutic effect on functional dystonia. Patient 1 showed a good and sustained therapeutic response, Patient 2 experienced a resolution of the dystonic posture that lasted for 10 days, and Patient 3 experienced no effect. Motor blocks may be a useful therapeutic option in chronic treatment-resistant functional dystonia. The treatment effect might be achieved through the experience of normal positioning and functioning of the limb.

Keywords: FND; functional dystonia; motor blocks; resistant chronic functional dystonia; treatment.

Publication types

  • Case Reports

MeSH terms

  • Dystonia* / drug therapy
  • Dystonic Disorders* / complications
  • Dystonic Disorders* / drug therapy
  • Humans
  • Movement Disorders* / complications
  • Upper Extremity