Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report

Clin Case Rep. 2023 Nov 27;11(12):e8186. doi: 10.1002/ccr3.8186. eCollection 2023 Dec.

Abstract

Drug-induced acute pancreatitis is a potentially ignored diagnosis that must be precisely valued. Drug-induced acute pancreatitis can be considered the third common cause of acute pancreatitis after ruling out alcohol and gallstones. Levofloxacin belongs to a class of fluoroquinolone antibiotics used for treating various infections. Besides photosensitivity and liver toxicity, levofloxacin can induce acute pancreatitis, although rarely described. We highlight a case of acute pancreatitis in a female induced by levofloxacin. She presented with typical signs and symptoms of acute pancreatitis and had been taking levofloxacin for urinary tract infections for the last 3 days. After ruling out all other possible causes, her clinical picture, laboratory results, and imaging findings confirmed acute pancreatitis induced by levofloxacin.

Keywords: abdominal ultrasonography; computed tomography; drug‐induced acute pancreatitis; fluoroquinolone; levofloxacin; photosensitivity.

Publication types

  • Case Reports