Minimizing Metabolic and Cardiac Risk Factors to Maximize Outcomes After Liver Transplantation

Kathryn Schmidt; Ashley Spann; Mohammad Qasim Khan; Manhal Izzy; Kymberly D Watt

doi:10.1097/TP.0000000000004875

Minimizing Metabolic and Cardiac Risk Factors to Maximize Outcomes After Liver Transplantation

Transplantation. 2024 Aug 1;108(8):1689-1699. doi: 10.1097/TP.0000000000004875. Epub 2023 Dec 7.

Authors

Kathryn Schmidt¹, Ashley Spann², Mohammad Qasim Khan³, Manhal Izzy², Kymberly D Watt¹

Affiliations

¹ Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.
² Division of Gastroenterology and Hepatology, Vanderbilit University, Nashville, TN.
³ Division of Gastroenterology and Hepatology, University of Western Ontario, London, ON, Canada.

PMID: 38060378
DOI: 10.1097/TP.0000000000004875

Abstract

Cardiovascular disease (CVD) is a leading complication after liver transplantation and has a significant impact on patients' outcomes posttransplant. The major risk factors for post-liver transplant CVD are age, preexisting CVD, nonalcoholic fatty liver disease, chronic kidney disease, and metabolic syndrome. This review explores the contemporary strategies and approaches to minimizing cardiometabolic disease burden in liver transplant recipients. We highlight areas for potential intervention to reduce the mortality of patients with metabolic syndrome and CVD after liver transplantation.

Publication types

Review

MeSH terms

Cardiovascular Diseases* / epidemiology
Cardiovascular Diseases* / etiology
Cardiovascular Diseases* / prevention & control
Heart Disease Risk Factors
Humans
Liver Transplantation* / adverse effects
Metabolic Syndrome* / epidemiology
Non-alcoholic Fatty Liver Disease / mortality
Non-alcoholic Fatty Liver Disease / surgery
Risk Assessment
Risk Factors
Treatment Outcome