Schizophrenia spectrum disorder (SSD) is a neurobiological illness that causes considerable deficits in body functions and activity participation. This study examined the effects of a computerized cognitive training (CCT) on cognition, motor functions and activity participation with a quasi-experimental, pretest-posttest design. A total of 14 patients participated. All participants underwent two stages of CCT but one did not complete the posttest. The training was 3 times a week, 40 minutes each time and lasted for 12 weeks. Cognition, upper extremity motor, postural control performance, and activity participation (work behavior) were measured at three times: before and after 6 and 12 weeks of training. CCT improved participant's cognition and work behavior significantly and have the tendency to improve motor function. The training dosage might be insufficient for motor function improvement.Clinical Relevance- SSD patients benefit from the CCT in cognition and work behavior significantly but Motor function slightly.