Peripartum Lipid Apheresis: Novel Management of Familial Hyperlipidemia in Pregnancy

Kayle Shapero; Malamo Countouris; Irina Chibisov; Arun Jeyabalan; Kathryn Berlacher

doi:10.1016/j.jaccas.2023.102052

Peripartum Lipid Apheresis: Novel Management of Familial Hyperlipidemia in Pregnancy

JACC Case Rep. 2023 Dec 6:27:102052. doi: 10.1016/j.jaccas.2023.102052.

Authors

Kayle Shapero¹, Malamo Countouris¹, Irina Chibisov^{2

3}, Arun Jeyabalan⁴, Kathryn Berlacher¹

Affiliations

¹ Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
² Vitalant Specialty Lab and Therapeutics, Pittsburgh, Pennsylvania, USA.
³ Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
⁴ Department of Obstetrics and Gynecology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Abstract

Familial hypercholesterolemia (FH) is a genetic lipid disorder associated with early-onset severe cardiovascular disease. Many FH therapeutics have not been studied in pregnancy, and management of patients with FH through pregnancy is limited. We present a patient with FH who was safely treated through pregnancy with combination therapy.

Keywords: atherosclerosis; dyslipidemia; lipid metabolism disorders; pregnancy; triglycerides.

Publication types

Case Reports