A Case of Migration of a Hydrogel Spacer for Radiotherapy into the Pulmonary Artery

Acta Med Okayama. 2023 Dec;77(6):647-650. doi: 10.18926/AMO/66157.

Abstract

A 67-year-old man was referred to our hospital for the diagnosis and treatment of prostate cancer. Multidisciplinary discussion led to intensity-modulated radiotherapy preceded by hormone therapy. Before radiotherapy, a biodegradable hydrogel spacer (HS) was placed between the prostate and rectum to reduce radiation injury risk. Three weeks postplacement, pelvic magnetic resonance imaging revealed HS migration into the pelvic vein. Subsequent whole-body contrast-enhanced computed tomography (CECT) revealed HS migration into the pulmonary artery. The patient showed no symptoms or clinical signs. Radiotherapy was completed uneventfully. Complete absorption of the migrated HS was confirmed using CECT images 5 months postplacement.

Keywords: hydrogel spacer; prostate cancer; pulmonary embolism; radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Hydrogel, Polyethylene Glycol Dimethacrylate
  • Hydrogels*
  • Male
  • Prostate / pathology
  • Prostatic Neoplasms* / pathology
  • Pulmonary Artery / diagnostic imaging
  • Pulmonary Artery / pathology
  • Rectum / pathology

Substances

  • Hydrogels
  • Hydrogel, Polyethylene Glycol Dimethacrylate