Takayasu's arteritis associated with Crohn's disease treated with infliximab

Clin J Gastroenterol. 2024 Apr;17(2):281-285. doi: 10.1007/s12328-023-01904-9. Epub 2024 Jan 5.

Abstract

A 23-year-old woman presented with fever, diarrhea, bloody stools, and arthralgia that did not improve despite previous treatments and was diagnosed with Crohn's disease. Remission was achieved after the introduction of infliximab, nutritional therapy, and 5-aminosalicylic acid treatment. However, the patient's blood sedimentation rate remained elevated without symptom recurrence, except for abdominal pain in the following year. Aortic wall thickening in the thoracic descending aorta was also observed on computed tomography. Accumulation in the thoracic descending aorta and abdominal aorta was confirmed using positron emission tomography-computed tomography. The patient was diagnosed with Takayasu's arteritis. The patient's abdominal symptoms resolved, and her blood sedimentation rate normalized after steroid administration.

Keywords: Crohn’s disease; Infliximab; Takayasu’s arteritis.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain
  • Adult
  • Crohn Disease* / complications
  • Crohn Disease* / diagnosis
  • Crohn Disease* / drug therapy
  • Diarrhea
  • Female
  • Humans
  • Infliximab / therapeutic use
  • Takayasu Arteritis* / complications
  • Takayasu Arteritis* / diagnostic imaging
  • Takayasu Arteritis* / drug therapy
  • Young Adult

Substances

  • Infliximab