Dengue and chikungunya infections are increasing globally, especially in India. While the majority of patients settle with symptomatic management, some develop life-threatening complications. Here we discuss a case of co-infection between dengue virus (DENV-2) and chikungunya virus (CHIKV) in a young Indian male who presented with an acute febrile illness that progressed to multi-organ dysfunction involving the hepatic, nervous, respiratory, and hematological systems. We discuss the management of this complicated case and attempt to generate awareness regarding the severity of co-infection by these viruses.
Keywords: chikungunya; co-infection; dengue; dengue fever (df); dengue hemorrhagic fever (dhf); diffuse alveolar hemorrhage; encephalitis; hepatitis; multi-organ dysfunction; thrombocytopenia.
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