Antimicrobial approach of abdominal post-surgical infections

World J Gastrointest Surg. 2023 Dec 27;15(12):2674-2692. doi: 10.4240/wjgs.v15.i12.2674.

Abstract

Abdominal surgical site infections (SSIs) are infections that occur after abdominal surgery. They can be superficial, involving the skin tissue only, or more profound, involving deeper skin tissues including organs and implanted materials. Currently, SSIs are large global health problem with an incidence that varies significantly depending on the United Nations' Human Development Index. The purpose of this review is to provide a practical update on the latest available literature on SSIs, focusing on causative pathogens and treatment with an overview of the ongoing studies of new therapeutic strategies.

Keywords: Abdominal post-operative complications; Carbapenem-resistant Enterobacterales; Carbapenem-resistant Klebsiella; Multidrug resistance; Post-surgical infections; Surgical site infections.

Publication types

  • Review