Efficacy and safety of brexucabtagene autoleucel CAR T-cell therapy with BTK inhibitors in the treatment of relapsed mantle cell lymphoma with central nervous system involvement

Leuk Lymphoma. 2024 May;65(5):669-673. doi: 10.1080/10428194.2024.2304622. Epub 2024 Jan 22.
No abstract available

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Agammaglobulinaemia Tyrosine Kinase* / antagonists & inhibitors
  • Aged
  • Central Nervous System Neoplasms* / drug therapy
  • Central Nervous System Neoplasms* / therapy
  • Combined Modality Therapy
  • Female
  • Humans
  • Immunotherapy, Adoptive* / adverse effects
  • Immunotherapy, Adoptive* / methods
  • Lymphoma, Mantle-Cell* / drug therapy
  • Lymphoma, Mantle-Cell* / pathology
  • Lymphoma, Mantle-Cell* / therapy
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / drug therapy
  • Protein Kinase Inhibitors* / adverse effects
  • Protein Kinase Inhibitors* / therapeutic use
  • Receptors, Chimeric Antigen
  • Treatment Outcome

Substances

  • Agammaglobulinaemia Tyrosine Kinase
  • Protein Kinase Inhibitors
  • BTK protein, human
  • Receptors, Chimeric Antigen