Nod Factor Lipopolysaccharide Purification to Study Nitrogen-Fixing Bacteria Symbiosis with Legumes

Methods Mol Biol. 2024:2751:237-245. doi: 10.1007/978-1-0716-3617-6_16.

Abstract

Nod factors (NF) are lipochitooligosaccharides produced by nitrogen-fixing rhizobia bacteria. They are key components of the rhizobia-plant signaling exchange required for symbiosis. Thus, techniques to extract, detect, characterize, and purify NF are crucial for the identification of both rhizobial and plant mechanisms underlying nitrogen-fixing symbiosis. Here, we describe a method for NF detection using radiolabeling and thin-layer chromatography. Furthermore, we describe a technique for purifying NF for downstream analyses.

Keywords: Chromatography; Nitrogen fixation; Nod factors; Nodulation; Rhizobium-legume symbiosis.

MeSH terms

  • Fabaceae*
  • Lipopolysaccharides
  • Nitrogen
  • Nitrogen-Fixing Bacteria*
  • Rhizobium*
  • Symbiosis
  • Vegetables

Substances

  • Lipopolysaccharides
  • Nitrogen