Phase 2 trial of induction with dasatinib and consolidation with hyper-CVAD plus dasatinib followed by allografting for Ph-positive acute lymphoblastic leukemia in adults

Leuk Res. 2024 Feb:137:107438. doi: 10.1016/j.leukres.2024.107438. Epub 2024 Jan 17.
No abstract available

Keywords: Allo-HSCT; Dasatinib; Hyper-CVAD; Ph-positive ALL.

Publication types

  • Clinical Trial, Phase II
  • Letter

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Cyclophosphamide / therapeutic use
  • Dasatinib / therapeutic use
  • Dexamethasone / therapeutic use
  • Doxorubicin / therapeutic use
  • Humans
  • Philadelphia Chromosome
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
  • Transplantation, Homologous
  • Vincristine / therapeutic use

Substances

  • Dasatinib
  • Cyclophosphamide
  • Dexamethasone
  • Doxorubicin
  • Vincristine

Associated data

  • JPRN/jRCTs031180284