Thromboembolic Disease

Prim Care. 2024 Mar;51(1):65-82. doi: 10.1016/j.pop.2023.07.004. Epub 2023 Aug 26.

Abstract

Venous thromboembolism (VTE) encompasses deep vein thrombosis and pulmonary embolism, both of which can present on a spectrum from subtle symptoms to life- and limb-threatening emergencies. Some risk factors for VTE overlap cardiovascular risk factors and statin therapy can somewhat reduce the VTE risk. When presentations are not life-threatening, clinical prediction scores using the Well's criteria are best used to determine diagnostic testing. The mainstay of VTE treatment is anticoagulant therapy, although life- and limb-threatening presentations can also require thrombolytic therapy.

Keywords: Deep vein thrombosis; Diagnosis; Management; Prevention; Primary care; Pulmonary embolism; Venous thromboembolism.

Publication types

  • Review

MeSH terms

  • Anticoagulants / adverse effects
  • Anticoagulants / therapeutic use
  • Humans
  • Pulmonary Embolism* / diagnosis
  • Pulmonary Embolism* / drug therapy
  • Risk Factors
  • Venous Thromboembolism* / diagnosis
  • Venous Thromboembolism* / drug therapy
  • Venous Thrombosis* / diagnosis
  • Venous Thrombosis* / drug therapy

Substances

  • Anticoagulants