Increase in CD8⁺ Effector Memory T Cells Re-Expressing CD45RA Correlates with Intractability of Severe Alopecia Areata

J Invest Dermatol. 2024 Jul;144(7):1654-1657.e7. doi: 10.1016/j.jid.2024.01.006. Epub 2024 Jan 26.

Authors

Ryo Takahashi¹, Misaki Kinoshita-Ise², Yoshimi Yamazaki², Masahiro Fukuyama², Manabu Ohyama³

Affiliations

¹ Flow Cytometry Core Facility, Kyorin University Graduate School of Medicine, Tokyo, Japan.
² Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan.
³ Flow Cytometry Core Facility, Kyorin University Graduate School of Medicine, Tokyo, Japan; Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan. Electronic address: [email protected].

PMID: 38280481
DOI: 10.1016/j.jid.2024.01.006

No abstract available

Keywords: CD8 T cells; Intravenous corticosteroid pulse therapy; NKG7; Rapidly progressive alopecia areata; TEMRA.

Publication types

Letter

MeSH terms

Adult
Alopecia Areata* / immunology
Alopecia Areata* / metabolism
CD8-Positive T-Lymphocytes* / immunology
CD8-Positive T-Lymphocytes* / metabolism
Female
Humans
Immunologic Memory
Leukocyte Common Antigens* / metabolism
Male
Memory T Cells / immunology
Memory T Cells / metabolism
Middle Aged
Severity of Illness Index
Young Adult

Substances

Leukocyte Common Antigens