Beam quality correction factors for ionization chambers in a 0.35 T magnetic resonance (MR)-linac - A Monte Carlo study

Phys Med. 2024 Mar:119:103314. doi: 10.1016/j.ejmp.2024.103314. Epub 2024 Feb 8.

Abstract

Purpose: The purpose of this study was to directly calculate [Formula: see text] correction factors for four cylindrical ICs for a 0.35 T MR-linac using the Monte Carlo (MC) method.

Methods: A previously-validated TOPAS/GEANT4 MC head model of the 0.35 T MR-linac was employed. The MR-compatible Exradin A12, A1SL, A26, and A28 cylindrical ICs were modeled considering the dead volume in the air cavity. The [Formula: see text] correction factor was determined for initial electron energies of 5-7 MeV. The correction factor was calculated for all four angular orientations in the lateral plane. The impact of the 0.35 T magnetic field on the IC response was also investigated.

Results: The maximum beam quality dependence in the [Formula: see text] exhibited by the A12, A1SL, A26, and A28 ICs was 1.10 %, 2.17 %, 0.81 %, and 1.75 %, respectively, considering all angular orientations. The magnetic field dependence was < 1 % and the maximum [Formula: see text] correction was < 2 % when the detector was aligned along the direction of the magnetic field at 0° and 180° angles. The A12 IC over-responded up to 5.40 % for the orthogonal orientation. An asymmetry in the response of up to 8.30 % was noted for the A28 IC aligned at 90° and 270° angles.

Conclusions: A parallel orientation for the IC, with respect to the magnetic field, is recommended for reference dosimetry in MRgRT. Both over and under-response in the IC signal was noted for the orthogonal orientations, which is highly dependent on the cavity diameter, cavity length, and the dead volume.

Keywords: Beam quality correction factors; Ion chambers; MR-guided RT (MRgRT); Monte Carlo; Reference dosimetry.

MeSH terms

  • Magnetic Fields
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Monte Carlo Method
  • Particle Accelerators*
  • Radiometry* / methods
  • Relative Biological Effectiveness