Editorial: Advances in pluripotent stem cell-based in vitro models of the human heart for cardiac physiology, disease modeling and clinical applications

Maksymilian Prondzynski; Josè Manuel Pioner; Luca Sala; Milena Bellin; Viviana Meraviglia

doi:10.3389/fphys.2024.1378495

Editorial: Advances in pluripotent stem cell-based in vitro models of the human heart for cardiac physiology, disease modeling and clinical applications

Front Physiol. 2024 Feb 19:15:1378495. doi: 10.3389/fphys.2024.1378495. eCollection 2024.

Authors

Maksymilian Prondzynski^{1

2}, Josè Manuel Pioner³, Luca Sala^{4

5}, Milena Bellin^{6

7

8}, Viviana Meraviglia⁶

Affiliations

¹ Department of Cardiology, Boston Children's Hospital, Boston, MA, United States.
² Harvard Medical School, Boston, MA, United States.
³ Department of Biology, University of Florence, Florence, Italy.
⁴ Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy.
⁵ Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.
⁶ Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, Netherlands.
⁷ Department of Biology, University of Padua, Padua, Italy.
⁸ Veneto Institute of Molecular Medicine, Padua, Italy.

No abstract available

Keywords: disease modeling and treatment; hiPSC-derived cardiac cells; human cardiac pathophysiology; human induced pluripotent stem cell (hiPSC); multicellular 3D cardiac models.

Publication types

Editorial

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Netherlands Organisation for Health Research and Development ZonMW (PSIDER no. 10250022110004), the European Research Council (ERC-CoG Mini-HEART no. 101001746), NextGenerationEU—Funding proposals by the beneficiaries of the calls Marie Sklodowska-Curie Individual Fellowships—MSCA-IF (Project No. H45E22001210006), CARIPLO Foundation—Biomedical Research Conducted by Young Researchers (Project No. 2019-1691), Single Ventricle Research Fund (SVRF) Additional Ventures and the Italian Ministry of University and Research (MUR) under the PRIN funding program (Research Projects of Significant National Interest, Project No. 20223L2C9N).