Identification of the novel HLA-A*02:01:01:251 allele in a candidate bone marrow donor by next-generation sequencing

HLA. 2024 Mar;103(3):e15430. doi: 10.1111/tan.15430.

Authors

Ahmed Gaballa^{1

2

3}, Marie Schaffer¹, Per Marits¹, Torsten Eich¹

Affiliations

¹ Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.
² Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
³ Department of Clinical Biochemistry, National Liver Institute, Menoufia University, Shebeen El-Kom, Egypt.

PMID: 38445381
DOI: 10.1111/tan.15430

Abstract

A single nucleotide mismatch within intron 1 differentiates HLA-A*02:01:01:251 from the HLA-A*02:01:01:01 allele.

Keywords: HLA; NGS; allele; typing.

© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Bone Marrow*
HLA-A Antigens
High-Throughput Nucleotide Sequencing*
Humans
Introns

Substances

HLA-A Antigens