A multimodal submillimeter MRI atlas of the human cerebellum

Sci Rep. 2024 Mar 7;14(1):5622. doi: 10.1038/s41598-024-55412-y.

Abstract

The human cerebellum is engaged in a broad array of tasks related to motor coordination, cognition, language, attention, memory, and emotional regulation. A detailed cerebellar atlas can facilitate the investigation of the structural and functional organization of the cerebellum. However, existing cerebellar atlases are typically limited to a single imaging modality with insufficient characterization of tissue properties. Here, we introduce a multifaceted cerebellar atlas based on high-resolution multimodal MRI, facilitating the understanding of the neurodevelopment and neurodegeneration of the cerebellum based on cortical morphology, tissue microstructure, and intra-cerebellar and cerebello-cerebral connectivity.

MeSH terms

  • Attention
  • Cerebellum* / physiology
  • Cognition / physiology
  • Humans
  • Language
  • Magnetic Resonance Imaging* / methods