Possible association between lithium intoxication and Takotsubo syndrome

BMJ Case Rep. 2024 Mar 13;17(3):e257051. doi: 10.1136/bcr-2023-257051.

Authors

Mara Elisa Vasconcelos^{1

2}, David Mota^{3

2}, Tânia Silva^{3

4}

Affiliations

¹ Psychiatry, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal [email protected].
² University of Coimbra Institute of Psychological Medicine, Coimbra, Portugal.
³ Psychiatry, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal.
⁴ University of Coimbra Faculty of Medicine, Coimbra, Portugal.

PMID: 38479830
PMCID: PMC10941129 (available on 2026-03-13)
DOI: 10.1136/bcr-2023-257051

Abstract

More than 25 years after being diagnosed with bipolar disorder and receiving continuous treatment with lithium, a woman develops Takotsubo syndrome.

Keywords: Bipolar I disorder; Drug interactions; Psychiatry of old age.

© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.

Publication types

Case Reports

MeSH terms

Antidepressive Agents / therapeutic use
Bipolar Disorder* / complications
Bipolar Disorder* / drug therapy
Female
Humans
Lithium / therapeutic use
Lithium Compounds / adverse effects
Takotsubo Cardiomyopathy* / chemically induced
Takotsubo Cardiomyopathy* / complications
Takotsubo Cardiomyopathy* / diagnosis

Substances

Lithium
Antidepressive Agents
Lithium Compounds