Patterns of Undertreatment and Overtreatment in Adjuvant Radiotherapy for Early-Stage Endometrial Cancer Based on Molecular Classification

Otilia Ciobanu; Yixuan He; Alicia R Martin; Jill S Remick; Joseph W Shelton; Tony Y Eng; David C Qian

doi:10.1001/jamaoncol.2024.0104

Patterns of Undertreatment and Overtreatment in Adjuvant Radiotherapy for Early-Stage Endometrial Cancer Based on Molecular Classification

JAMA Oncol. 2024 May 1;10(5):671-674. doi: 10.1001/jamaoncol.2024.0104.

Authors

Otilia Ciobanu¹, Yixuan He², Alicia R Martin², Jill S Remick³, Joseph W Shelton³, Tony Y Eng³, David C Qian^{3

4}

Affiliations

¹ Department of Radiation Oncology, The Oncology Institute Al Trestioreanu, Bucharest, Romania.
² Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston.
³ Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
⁴ Department of Thoracic Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston.

PMID: 38483373
PMCID: PMC10941016 (available on 2025-03-14)
DOI: 10.1001/jamaoncol.2024.0104

No abstract available

Plain language summary

The quality improvement study examines the use of risk-adaptive adjuvant radiotherapy in women with non–mismatch repair deficiency endometrial cancer.

MeSH terms

Aged
Endometrial Neoplasms* / pathology
Endometrial Neoplasms* / radiotherapy
Female
Humans
Medical Overuse
Middle Aged
Neoplasm Staging*
Radiotherapy, Adjuvant
Undertreatment