Computer assessment of hemodynamic severity of coronary artery stenosis from angiograms

Comput Methods Programs Biomed. 1985 Nov;21(2):143-52. doi: 10.1016/0169-2607(85)90075-6.

Abstract

A computer-assisted analysis of coronary obstructions from cineangiograms is presented, which includes both the geometric and hemodynamic evaluation of coronary stenosis severity. Single frame images are digitized into a 512 X 512 X 8 bit array after a cine-to-video conversion. Automatic edge tracking is performed using a combination of derivative and threshold methods. Vessel borders from two orthogonal views of the arterial segment are used to create a three-dimensional reconstruction of the stenosis, which serves as a basis for calculation of absolute and relative geometric dimensions, stenotic resistance and trans-stenotic pressure gradient for various given flow rates. A preliminary performance evaluation of this method was made by analysis of x-ray phantoms representing stenoses of known dimensions, which were filmed under quasi-clinical conditions. The results are discussed with respect to their accuracy and reproducibility.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cineangiography*
  • Computers*
  • Constriction, Pathologic / diagnostic imaging
  • Constriction, Pathologic / physiopathology
  • Coronary Angiography*
  • Coronary Vessels / pathology
  • Coronary Vessels / physiopathology
  • Evaluation Studies as Topic
  • Hemodynamics*
  • Humans
  • Models, Anatomic