Respiratory oscillometry with CT image analysis in idiopathic pulmonary fibrosis following single lung transplant

Joyce K Y Wu; Jessica Jia-Ni Xu; Anastasiia Vasileva; Cynthia Nohra; Matthew Binnie; Shane Shapera; Jolene H Fisher; Clodagh M Ryan; Micheal McInnis; Zoltán Hantos; Chung-Wai Chow

doi:10.1016/j.rmcr.2024.102016

Respiratory oscillometry with CT image analysis in idiopathic pulmonary fibrosis following single lung transplant

Respir Med Case Rep. 2024 Mar 22:49:102016. doi: 10.1016/j.rmcr.2024.102016. eCollection 2024.

Authors

Joyce K Y Wu^{1

2}, Jessica Jia-Ni Xu¹, Anastasiia Vasileva¹, Cynthia Nohra¹, Matthew Binnie^{1

3

4}, Shane Shapera^{1

4}, Jolene H Fisher^{1

4}, Clodagh M Ryan^{1

2}, Micheal McInnis⁵, Zoltán Hantos⁶, Chung-Wai Chow^{1

3}

Affiliations

¹ Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada.
² Toronto General-Pulmonary Function Laboratory, University Health Network, Toronto, Canada.
³ Toronto Lung Transplant Program, University Health Network, Toronto, Canada.
⁴ Interstitial Lung Disease Program, University Health Network, Toronto, Canada.
⁵ Joint Department of Medical Imaging, University Health Network, Toronto, Canada.
⁶ Department of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.

Abstract

Oscillometry is an emerging pulmonary function testing tool that is conducted during tidal breaths with minimal patient effort. It is highly sensitive to changes in lung mechanics. Oscillometry was recently shown to be highly associated with disease severity in idiopathic pulmonary fibrosis (IPF). The usefulness of oscillometry after single lung transplant in IPF patients is not well understood. Our study demonstrated that oscillometry can detect changes in the graft despite presence of a native fibrotic lung to provide useful information to complement spirometry.

Publication types

Case Reports