Alcohol associated liver disease and bariatric surgery: Current perspectives and future directions

World J Gastrointest Surg. 2024 Mar 27;16(3):650-657. doi: 10.4240/wjgs.v16.i3.650.

Abstract

Bariatric surgery is a routinely performed procedure and is associated with a reduction in all-cause mortality in patients with obesity. However, bariatric surgery has also been linked to increased alcohol use with up to 30% of these patients developing alcohol use disorder (AUD). The mechanism of AUD after bariatric surgery is multifactorial and includes anatomic, metabolic, and neurohumoral changes associated with post-surgical anatomy. These patients are at increased risk of alcohol associated liver disease and, in some cases, require liver transplantation. In this article, we provide a scoping review of epidemiology, pathophysiology, and clinical outcomes of alcohol-related health conditions after bariatric surgery.

Keywords: Alcohol use disorder; Liver transplant; Obesity medicine; Roux-en-Y gastric bypass; Simultaneous liver transplant and bariatric surgery; Vertical sleeve gastrectomy.

Publication types

  • Review