Multimodality imaging in arrhythmogenic cardiomyopathy - From diagnosis to management

Giulia Mattesi; Valeria Pergola; Riccardo Bariani; Marika Martini; Raffaella Motta; Martina Perazzolo Marra; Ilaria Rigato; Barbara Bauce

doi:10.1016/j.ijcard.2024.132023

Multimodality imaging in arrhythmogenic cardiomyopathy - From diagnosis to management

Int J Cardiol. 2024 Jul 15:407:132023. doi: 10.1016/j.ijcard.2024.132023. Epub 2024 Apr 5.

Authors

Giulia Mattesi¹, Valeria Pergola², Riccardo Bariani³, Marika Martini³, Raffaella Motta⁴, Martina Perazzolo Marra³, Ilaria Rigato¹, Barbara Bauce³

Affiliations

¹ Azienda Ospedale Università Padova, Italy.
² Azienda Ospedale Università Padova, Italy. Electronic address: [email protected].
³ Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padova, Italy.
⁴ Department of Medicine, University of Padova, Italy.

PMID: 38583594
DOI: 10.1016/j.ijcard.2024.132023

Abstract

Arrhythmogenic Cardiomyopathy (AC), an inherited cardiac disorder characterized by myocardial fibrofatty replacement, carries a significant risk of sudden cardiac death (SCD) due to ventricular arrhythmias. A comprehensive multimodality imaging approach, including echocardiography, cardiac magnetic resonance imaging (CMR), and cardiac computed tomography (CCT), allows for accurate diagnosis, effective risk stratification, vigilant monitoring, and appropriate intervention, leading to improved patient outcomes and the prevention of SCD. Echocardiography is primary tool ventricular morphology and function assessment, CMR provides detailed visualization, CCT is essential in early stages for excluding congenital anomalies and coronary artery disease. Echocardiography is preferred for follow-up, with CMR capturing changes over time. The strategic use of these imaging methods aids in confirming AC, differentiating it from other conditions, tracking its progression, managing complications, and addressing end-stage scenarios.

Keywords: Advanced echocardiography; Arrhythmogenic cardiomyopathy; Cardiac computed tomography; Cardiac magnetic resonance; Echocardiography; Multimodality imaging.

Publication types

Review

MeSH terms

Arrhythmogenic Right Ventricular Dysplasia* / diagnosis
Arrhythmogenic Right Ventricular Dysplasia* / diagnostic imaging
Arrhythmogenic Right Ventricular Dysplasia* / physiopathology
Arrhythmogenic Right Ventricular Dysplasia* / therapy
Death, Sudden, Cardiac / etiology
Death, Sudden, Cardiac / prevention & control
Disease Management
Echocardiography / methods
Humans
Magnetic Resonance Imaging, Cine / methods
Multimodal Imaging* / methods