Short-term and long-term outcomes of on-pump beating-heart coronary artery bypass surgery in dialysis and non-dialysis patients: a retrospective study in a single center

J Cardiothorac Surg. 2024 Apr 30;19(1):268. doi: 10.1186/s13019-024-02662-6.

Abstract

Background: This study aimed to evaluate the short-term and long-term outcomes of dialysis and non-dialysis patients after On-pump beating-heart coronary artery bypass grafting (OPBH-CABG).

Methods: We retrospectively reviewed medical records of 659 patients underwent OPBH-CABG at our hospital from 2009 to 2019, including 549 non-dialysis patients and 110 dialysis patients. Outcomes were in-hospital mortality, length of stay, surgical complications, post-CABG reintervention, and late mortality. The median follow-up was 3.88 years in non-dialysis patients and 2.24 years in dialysis patients. Propensity matching analysis was performed.

Results: After 1:1 matching, dialysis patients had significantly longer length of stay (14 (11-18) vs. 12 (10-15), p = 0.016), higher rates of myocardial infarction (16.85% vs. 6.74%, p = 0.037) and late mortality (25.93% vs. 9.4%, p = 0.005) after CABG compared to non-dialysis patients. No significant differences were observed in in-hospital mortality, complications, or post-CABG reintervention rate between dialysis and non-dialysis groups.

Conclusions: OPBH-CABG could achieve comparable surgical mortality, surgical complication rates, and long-term revascularization in dialysis patients as those in non-dialysis patients. The results show that OPBH-CABG is a safe and effective surgical option for dialysis patients.

Keywords: Coronary artery bypass grafting (CABG); Dialysis; Mortality; Myocardial infarction; On-pump beating-heart.

MeSH terms

  • Aged
  • Coronary Artery Bypass* / methods
  • Coronary Artery Bypass* / mortality
  • Coronary Artery Disease* / complications
  • Coronary Artery Disease* / mortality
  • Coronary Artery Disease* / surgery
  • Female
  • Hospital Mortality*
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Postoperative Complications* / epidemiology
  • Renal Dialysis*
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome