CAR-T overdrive: harnessing inosine for metabolic rewiring and stemness induction

Signal Transduct Target Ther. 2024 May 7;9(1):120. doi: 10.1038/s41392-024-01818-z.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Letter

MeSH terms

  • Animals
  • Humans
  • Immunotherapy, Adoptive
  • Inosine* / genetics
  • Inosine* / metabolism
  • Neoplastic Stem Cells / metabolism
  • Neoplastic Stem Cells / pathology
  • Receptors, Chimeric Antigen / genetics
  • Receptors, Chimeric Antigen / immunology

Substances

  • Inosine
  • Receptors, Chimeric Antigen