Abstract
In addition to T-cell defects AIDS shows a separate B-cell dysfunction. Elevated spontaneous IgG-levels (not IgM) and a lacking proliferative and differentiation response to polyclonal B-cell activators can be demonstrated in vitro.
MeSH terms
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Acquired Immunodeficiency Syndrome / immunology*
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B-Lymphocytes / immunology*
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Homosexuality
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Humans
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Immunoglobulin G / metabolism
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Immunoglobulin M / metabolism
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Lymphocyte Activation
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Male
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Risk
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T-Lymphocytes / immunology*
Substances
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Immunoglobulin G
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Immunoglobulin M